clorazepate (Tranxene®)

What is clorazepate (tranxene®)?

Clorazepate (tranxene®) is a medication that belongs to a class of drugs called benzodiazepines. It is primarily used to treat anxiety and insomnia. Clorazepate works by enhancing the activity of a neurotransmitter called GABA in the brain, which leads to a calming effect and helps reduce anxiety and promote sleep. It is also used to help control seizures, as a muscle relaxant and as an anticonvulsant agent. It is available in tablet and capsule form and it is usually taken 2-3 times a day. The medication should be used only under the supervision of a healthcare provider. And it’s a controlled substance.

Clorazepate dosage.

Clorazepate (tranxene®) is available in several different forms, including:

• Tablets: Available in 3.75mg, 7.5mg, and 15mg strengths.
• Capsules: Available in 7.5mg and 15mg strengths.
• Liquid: Available in a 15mg/5mL strength.

Dosage is usually determined by a healthcare provider, and it varies depending on the individual’s medical condition, response to treatment, and other factors. It is important to follow the dosing instructions provided by your healthcare provider and not to exceed the recommended dosage. The usual adult dose for anxiety is 3.75 mg to 15 mg two to three times a day. For insomnia, it is 7.5 mg to 30 mg at bedtime.

It is important to note that clorazepate can be habit-forming, and withdrawal symptoms can occur if the medication is suddenly stopped. Therefore, the dosage should be gradually decreased under the guidance of a healthcare provider.

Clorazepate uses

Clorazepate (tranxene®) is primarily used to treat anxiety and insomnia. Some of the specific uses of clorazepate include:

• Anxiety: Clorazepate is used to relieve symptoms of anxiety, such as nervousness, tension, and agitation.
• Insomnia: Clorazepate is used as a sedative to help people fall asleep and stay asleep.
• Seizures: Clorazepate is used to control certain types of seizures, such as petit mal seizures, and as an adjunctive therapy for the treatment of grand mal seizures.
• Alcohol withdrawal: Clorazepate may be used to reduce the symptoms of alcohol withdrawal, such as tremors, agitation, and seizures.

It is used under the supervision of a healthcare provider, and it should be used only for the condition for which it was prescribed. It’s important to note that clorazepate can cause drowsiness and impair judgment, thinking, and motor skills, so it should be used with caution if operating heavy machinery or driving.

How to use

Clorazepate (tranxene®) should be used only as directed by a healthcare provider. The following are general guidelines for using clorazepate:

• Take clorazepate with a full glass of water, with or without food.
• Take clorazepate at the same time each day to maintain a consistent level of the medication in your body.
• Do not crush, chew, or break the tablets or capsules. Swallow them whole.
• If you are using the liquid form of clorazepate, measure the medication with a measuring spoon or dropper, not with a regular table spoon.
• Follow the dosing instructions provided by your healthcare provider. Do not take more or less than prescribed.
• Do not stop taking clorazepate suddenly, as withdrawal symptoms can occur. Your healthcare provider may gradually decrease your dose over time.
• If you miss a dose of clorazepate, take it as soon as you remember. However, if it is close to the time for your next dose, do not take the missed dose. Just resume your regular dosing schedule.
• Keep a record of the amount of medication used from each new bottle. Clorazepate is a controlled substance and it should be kept in a safe place to prevent misuse and abuse.
• Consult with your healthcare provider if you have any questions about the use of clorazepate.

Clorazepate side effects.

Clorazepate (tranxene®) can cause side effects, although not everyone who takes the medication will experience them. Some of the most common side effects of clorazepate include:

• Drowsiness and sedation: Clorazepate can cause drowsiness and sedation, which may impair your ability to drive or operate heavy machinery.
• Dizziness: Clorazepate can cause dizziness, which may impair your ability to walk or stand.
• Coordination problems: Clorazepate can cause coordination problems, which may impair your ability to perform fine motor tasks.
• Memory problems: Clorazepate can cause memory problems, which may impair your ability to remember events that occurred while you were taking the medication.
• Blurred vision: Clorazepate can cause blurred vision, which may impair your ability to see clearly.
• Constipation: Clorazepate can cause constipation, which may make it difficult to have bowel movements.
• Dry mouth: Clorazepate can cause dry mouth, which may make it difficult to speak or swallow.
• Skin rash: Clorazepate can cause skin rash, which may be itchy or painful.

These are not all the possible side effects of clorazepate. If you experience any unusual symptoms while taking clorazepate, contact your healthcare provider. It is important to report any side effects to your healthcare provider.

Clorazepate warnings & Precautions.

Clorazepate storage.

Clorazepate (tranxene®) should be stored at room temperature, away from heat, light, and moisture. The medication should be kept in a secure location and out of the reach of children and pets.

When storing the liquid form of clorazepate, it should be shaken well before each use and protected from freezing.

It is important to dispose of unused, expired, or unwanted medications properly, to prevent misuse and abuse. You can contact your healthcare provider or pharmacist for information on safe disposal methods for your medication.

It’s also a controlled substance and should be kept in a safe place, to prevent misuse and abuse.

It is important to keep track of the amount of medication used from each new bottle and to notify your healthcare provider if you notice any missing medication.

Clorazepate interactions.

Clorazepate (tranxene®) can interact with other medications, which can increase the risk of side effects or make the medications less effective. It is important to tell your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter drugs, vitamins, and herbal supplements.

Some of the medications that may interact with clorazepate include:

• Opioids: Clorazepate may increase the sedative effects of opioids, such as morphine and codeine.
• Anti-anxiety medications: Clorazepate may increase the sedative effects of other anti-anxiety medications, such as alprazolam (Xanax) and diazepam (Valium).
• Antidepressants: Clorazepate may increase the sedative effects of antidepressants, such as fluoxetine (Prozac) and sertraline (Zoloft).
• Sedatives: Clorazepate may increase the sedative effects of other sedative medications, such as zolpidem (Ambien) and eszopiclone (Lunesta).
• Antihistamines: Clorazepate may increase the sedative effects of antihistamines, such as diphenhydramine (Benadryl) and cetirizine (Zyrtec).
• Narcotics: Clorazepate may increase the sedative effects of narcotic medications, such as fentanyl and oxycodone.

It is important to inform your healthcare provider if you are taking any of these medications or any other medications, as well as if you are taking any herbal supplements or vitamins. In case of any changes in your medication list, inform your healthcare provider as well.

Clorazepate vs xanax.

Clorazepate (tranxene®) and clonazepam (klonopin®) are both medications that belong to the class of drugs called benzodiazepines. They are both used to treat anxiety, insomnia and also used to control seizures. However, there are some differences between the two medications.

• Indications: Clorazepate is also used as a muscle relaxant and as an adjunctive therapy for the treatment of grand mal seizures. While clonazepam is primarily used for the management of anxiety disorders, panic disorder, and seizure disorders.
• Dosage: Clorazepate is available in 3.75mg, 7.5mg, and 15mg tablets and liquid forms. Clonazepam is available in 0.5mg, 1mg, and 2mg tablets.
• Duration of Action: Clorazepate has a longer half-life than Clonazepam, it may have a longer duration of action, which means that its effects may last longer.
• Withdrawal: Withdrawal symptoms can occur if clorazepate or clonazepam is suddenly stopped. These symptoms can include insomnia, irritability, and seizures. Withdrawal symptoms can also include rebound anxiety and insomnia, headaches, and muscle pain.
• Interactions: Clorazepate may interact with other medications such as opioids, antihistamines, antidepressants, and sedatives. Clonazepam also may interact with other medications such as opioids, antihistamines, antidepressants, and sedatives as well.

Both medications can have side effects, and it is important to follow the instructions of your healthcare provider and to report any side effects or concerns to them. It’s also important to note that both are controlled substances, and they should be used only under the guidance of a healthcare provider.

Clorazepate overdose.

An overdose of clorazepate (tranxene®) can be serious and may cause life-threatening symptoms. If you suspect an overdose, seek immediate medical attention.

Symptoms of a clorazepate overdose may include:

• Drowsiness
• Confusion
• Unconsciousness
• Coma
• Slurred speech
• Coordination problems
• Blurred vision
• Respiratory depression
• Seizures
• Shock

If you overdose on clorazepate, you may be given medications to reverse the effects of the drug and to prevent seizures. You may also be given supportive care, such as oxygen, to help you breathe.

It is important to keep clorazepate and all medications out of reach of children and to dispose of any unused or expired medications properly. If you suspect someone has taken an overdose of clorazepate, call for emergency medical help right away.